Index: wp-includes/js/mediaelement/wp-mediaelement.js
===================================================================
--- wp-includes/js/mediaelement/wp-mediaelement.js	(revision 24935)
+++ wp-includes/js/mediaelement/wp-mediaelement.js	(working copy)
@@ -3,8 +3,13 @@
 	mejs.plugins.silverlight[0].types.push('video/x-ms-wmv');
 	mejs.plugins.silverlight[0].types.push('audio/x-ms-wma');
 
-    $(function () {
-		$('.wp-audio-shortcode, .wp-video-shortcode').mediaelementplayer();
+	$(function () {
+		var settings = {};
+
+		if ( typeof wpmejsL10n !== 'undefined' )
+			settings.pluginPath = wpmejsL10n.pluginPath;
+
+		$('.wp-audio-shortcode, .wp-video-shortcode').mediaelementplayer( settings );
 	});
 
-}(jQuery));
\ No newline at end of file
+}(jQuery));
Index: wp-includes/script-loader.php
===================================================================
--- wp-includes/script-loader.php	(revision 24935)
+++ wp-includes/script-loader.php	(working copy)
@@ -302,6 +302,9 @@
 
 
 	$scripts->add( 'wp-mediaelement', "/wp-includes/js/mediaelement/wp-mediaelement.js", array('mediaelement'), false, 1 );
+	did_action( 'init' ) && $scripts->localize( 'wp-mediaelement', 'wpmejsL10n', array(
+		'pluginPath' => includes_url( 'js/mediaelement/' ),
+	) );
 
 	$scripts->add( 'password-strength-meter', "/wp-admin/js/password-strength-meter$suffix.js", array('jquery'), false, 1 );
 	did_action( 'init' ) && $scripts->localize( 'password-strength-meter', 'pwsL10n', array(