Index: src/wp-admin/includes/class-wp-media-list-table.php
===================================================================
--- src/wp-admin/includes/class-wp-media-list-table.php	(revision 32619)
+++ src/wp-admin/includes/class-wp-media-list-table.php	(working copy)
@@ -316,12 +316,19 @@
 		$attributes = 'class="column-icon media-icon ' . $mime . '-icon"' . $style;
 ?>
 		<td <?php echo $attributes ?>><?php
-			if ( $thumb = wp_get_attachment_image( $post->ID, array( 80, 60 ), true ) ) {
+			if ( $this->is_trash || ! $user_can_edit ) {
+				// Preserve the original alt attribute for non-linked images.
+				$thumb_attr = '';
+			} else {
+				// For linked images the alt attribute should communicate the destination of the link or action taken.
+				$thumb_attr = array( 'alt' => esc_attr( sprintf( __( 'Edit &#8220;%s&#8221;' ), $att_title ) ) );
+			}
+			if ( $thumb = wp_get_attachment_image( $post->ID, array( 80, 60 ), true, $thumb_attr ) ) {
 				if ( $this->is_trash || ! $user_can_edit ) {
 					echo $thumb;
 				} else {
 ?>
-				<a href="<?php echo get_edit_post_link( $post->ID ); ?>" title="<?php echo esc_attr( sprintf( __( 'Edit &#8220;%s&#8221;' ), $att_title ) ); ?>">
+				<a href="<?php echo get_edit_post_link( $post->ID ); ?>">
 					<?php echo $thumb; ?>
 				</a>
 
@@ -338,12 +345,13 @@
 			<?php if ( $this->is_trash || ! $user_can_edit ) {
 				echo $att_title;
 			} else { ?>
-			<a href="<?php echo get_edit_post_link( $post->ID ); ?>"
-				title="<?php echo esc_attr( sprintf( __( 'Edit &#8220;%s&#8221;' ), $att_title ) ); ?>">
-				<?php echo $att_title; ?></a>
+			<a href="<?php echo get_edit_post_link( $post->ID ); ?>">
+				<span aria-hidden="true"><?php echo $att_title; ?></span>
+				<span class="screen-reader-text"><?php echo esc_attr( sprintf( __( 'Edit &#8220;%s&#8221;' ), $att_title ) ); ?></span>
+			</a>
 			<?php };
 			_media_states( $post ); ?></strong>
-			<p class="filename"><?php echo wp_basename( $post->guid ); ?></p>
+			<p class="filename"><span class="screen-reader-text"><?php _e( 'File name:' ); ?> </span><?php echo wp_basename( $post->guid ); ?></p>
 <?php
 		echo $this->row_actions( $this->_get_row_actions( $post, $att_title ) );
 ?>