Index: src/wp-admin/js/color-picker.js
===================================================================
--- src/wp-admin/js/color-picker.js	(revision 39362)
+++ src/wp-admin/js/color-picker.js	(working copy)
@@ -160,7 +160,11 @@
 			$( 'body' ).trigger( 'click.wpcolorpicker' ).on( 'click.wpcolorpicker', this.close );
 		},
 		close: function() {
-			this.element.hide().iris( 'toggle' );
+			this.element.hide();
+			// if iris hasn't already been destroyed
+			if ( this.element.iris( 'instance' ) ) {
+				this.element.iris( 'toggle' );
+			}
 			this.button.addClass( 'hidden' );
 			this.wrap.removeClass( 'wp-picker-active' );
 			this.toggler.removeClass( 'wp-picker-open' );
Index: tests/qunit/index.html
===================================================================
--- tests/qunit/index.html	(revision 39362)
+++ tests/qunit/index.html	(working copy)
@@ -50,11 +50,14 @@
 		<script type='text/javascript' src='../../src/wp-includes/js/jquery/ui/sortable.js'></script>
 		<script type='text/javascript' src='../../src/wp-includes/js/jquery/ui/draggable.js'></script>
 		<script type='text/javascript' src='../../src/wp-includes/js/jquery/ui/droppable.js'></script>
+		<script type='text/javascript' src='../../src/wp-includes/js/jquery/ui/slider.js'></script>
 
 		<script src="../../src/wp-admin/js/nav-menu.js"></script>
 		<script src="../../src/wp-admin/js/customize-nav-menus.js"></script>
 		<script src="../../src/wp-admin/js/customize-widgets.js"></script>
 		<script src="../../src/wp-admin/js/word-count.js"></script>
+		<script src="../../src/wp-admin/js/iris.min.js"></script>
+		<script src="../../src/wp-admin/js/color-picker.js"></script>
 
 		<!-- Unit tests -->
 		<script src="wp-admin/js/password-strength-meter.js"></script>
@@ -66,6 +69,7 @@
 		<script src="wp-admin/js/customize-nav-menus.js"></script>
 		<script src="wp-admin/js/customize-widgets.js"></script>
 		<script src="wp-admin/js/word-count.js"></script>
+		<script src="wp-admin/js/color-picker.js"></script>
 
 		<!-- Customizer templates for sections -->
 		<script type="text/html" id="tmpl-customize-section-default">
Index: tests/qunit/wp-admin/js/color-picker.js
===================================================================
--- tests/qunit/wp-admin/js/color-picker.js	(nonexistent)
+++ tests/qunit/wp-admin/js/color-picker.js	(working copy)
@@ -0,0 +1,30 @@
+/* global jQuery */
+jQuery( function() {
+	module( 'color-picker', {
+		setup: function() {
+			window.wpColorPickerL10n = window.wpColorPickerL10n || {
+				clear: 'Clear',
+				defaultString: 'Default',
+				pick: 'Select Color',
+				current: 'Current Color'
+			};
+			jQuery( document.body ).append( '<div id="color-picker-container" style="position:absolute; left:-1000px;"><input id="color-picker" name="color-picker" type="text"></div>' );
+		},
+		teardown: function() {
+			jQuery( '#color-picker-container' ).remove();
+		}
+	} );
+
+	// #32856
+	test( 'close should check that iris hasn\'t been destroyed before toggling it', function() {
+
+		var $input = jQuery( 'input#color-picker' );
+		$input.wpColorPicker();
+
+		$input.iris( 'destroy' );
+		notOk( $input.iris( 'instance' ) );
+
+		$input.wpColorPicker( 'close' );
+		notOk( $input.wpColorPicker( 'instance' ).toggler.hasClass( 'wp-picker-open' ), 'close completed' );
+	});
+});