diff --git src/wp-admin/includes/admin-filters.php src/wp-admin/includes/admin-filters.php
index c080fd0f24..e62dd13780 100644
--- src/wp-admin/includes/admin-filters.php
+++ src/wp-admin/includes/admin-filters.php
@@ -148,3 +148,6 @@ add_action( 'post_updated', array( 'WP_Privacy_Policy_Content', '_policy_page_up
 
 // Append '(Draft)' to draft page titles in the privacy page dropdown.
 add_filter( 'list_pages', '_wp_privacy_settings_filter_draft_page_titles', 10, 2 );
+
+// Show warning notice on wp-admin/options.php page.
+add_action( 'admin_notices', 'wp_admin_options_php_page_warning_admin_notice' );
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diff --git src/wp-admin/includes/options.php src/wp-admin/includes/options.php
index 7911abcfba..fc5d5261f5 100644
--- src/wp-admin/includes/options.php
+++ src/wp-admin/includes/options.php
@@ -131,3 +131,22 @@ function options_reading_blog_charset() {
 	echo '<input name="blog_charset" type="text" id="blog_charset" value="' . esc_attr( get_option( 'blog_charset' ) ) . '" class="regular-text" />';
 	echo '<p class="description">' . __( 'The <a href="https://wordpress.org/support/article/glossary/#character-set">character encoding</a> of your site (UTF-8 is recommended)' ) . '</p>';
 }
+
+/**
+ * Display a warning notice to admin to be careful inside the options.php.
+ *
+ * @since 5.3
+ */
+function wp_admin_options_php_page_warning_admin_notice() {
+	global $pagenow;
+
+	if ( 'options.php' != $pagenow ) {
+		return;
+	}
+	
+	echo '<div class="notice notice-warning">';
+	echo '<p><strong>' . __( 'WARNING!' ) . '</strong></p>';
+    echo '<p>' . __( 'This page allows direct access to your site settings. You can break things here. Please be cautious!' ) . '</p>';
+    echo '</div>';
+
+}
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