diff --git a/src/js/_enqueues/admin/edit-comments.js b/src/js/_enqueues/admin/edit-comments.js
index 1a64268b6a..3aa833f914 100644
--- a/src/js/_enqueues/admin/edit-comments.js
+++ b/src/js/_enqueues/admin/edit-comments.js
@@ -793,7 +793,15 @@ window.commentReply = {
 		$( '.cancel', row ).click( function() { return commentReply.revert(); } );
 		$( '.save', row ).click( function() { return commentReply.send(); } );
 		$( 'input#author-name, input#author-email, input#author-url', row ).keypress( function( e ) {
-			if ( e.which == 13 ) {
+			if ( e.which === 13 ) {
+				commentReply.send();
+				e.preventDefault();
+				return false;
+			}
+		});
+
+		$( 'textarea#replycontent', row ).keypress( function( e ) {
+			if ( ( e.metaKey || e.ctrlKey ) && e.which === 13 ) {
 				commentReply.send();
 				e.preventDefault();
 				return false;
